会员登录.getTime()%>)
购物车()
首页>
生物试剂
成功收藏产品
商家描述
包装清单
售后服务
产品评价(0)
BAPTA是一种钙选择性螯合剂。它基本的螯合单位和EDTA类似，只是两个脂肪氮被芳香氮所替代。因此，BAPTA在生理pH下不会被质子化。BAPTA的pKa3为5.47，pKa4为6.36。这个特点显示了去质子化的步骤并不包含在Ca的螯合步骤中。由于不受质子的干扰，它的螯合率比EGTA要高很多。BAPTA-AM是BAPTA的乙酰甲酯衍生物，通过AM法，能被轻易负载到细胞中。BAPTA-AM对于细胞内钙离子的监控是非常有用的。
BAPTA, AM ester is a cell-permeant chelator, which is a highly selective for Ca2+ over Mg2+ , and it can be used to control the level of intracellular Ca2+. BAPTA is more selective for Ca2+ than EDTA and EGTA, and its metal binding is also less sensitive to pH.
Specifications
| Molecular Formula: | C34H40N2O18 |
|
| Molecular Weight: | 764.69 | |
| CAS Number: | 126150-97-8 | |
| Product Size: | 25 mg | |
| Storage Conditions: | -20°C | |
| Shipping Condition: | Room Temperature | |
|
Applications Calcium chelator |
||
| Datasheet (PDF): | BAPTA, AM-PDF（说明书点击下载） |
| MSDS (PDF): | MSDS-C203 |
References:
Tonotopic variations of calcium signalling in turtle auditory hair cells.Tonotopic variations of calcium signalling in turtle auditory hair cells.
Ricci AJ, Gray-Keller M, Fettiplace R
J Physiol (2000) 524 Pt 2:423-436
Product usage:
J Physiol (2000) 524 Pt 2:423-436
Product usage:
Cadherins mediate intercellular mechanical signaling in fibroblasts by activation of stretch-sensitive calcium-permeable channels.Cadherins mediate intercellular mechanical signaling in fibroblasts by activation of stretch-sensitive calcium-permeable channels.
Ko KS, Arora PD, McCulloch CA
J Biol Chem (2001) 276:35967-35977
Product usage:
J Biol Chem (2001) 276:35967-35977
Product usage:
A practical guide to the preparation of Ca2+ buffers.A practical guide to the preparation of Ca2+ buffers.
Bers DM, Patton CW, Nuccitelli R
Methods Cell Biol (1994) 40:3-29
Methods Cell Biol (1994) 40:3-29
