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| CatalogNo: | AP1199 |
| Brand: | ABclonal |
| ProductName: | Phospho-STING-S365 Rabbit pAb |
| Gene Symbol: | Sting1 |
| Alias: | ERIS; MPYS; Mita; STING; Tmem173; STING-beta; 2610307O08Rik |
| GeneId: | 72512 |
| Swiss-Prot: | Q3TBT3 |
| Routing: | Synthetic peptide |
| Species: | Mouse |
| ProteinWeight: | 43kDa |
| ObservedMW: | 41kDa |
| Source: | Rabbit |
| Immunogen: | A synthetic phosphorylated peptide around S365 of mouse STING (NP_082537.1). |
| AntigenSeq: | PRLLISGMDQP |
| CrossReactivity: | Human, Mouse |
| Application: | ELISA, WB |
| RecommandDilution: | WB,1:500 - 1:1000 |
| Storage: | Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| PositiveSamples: | THP-1 |
| CelluarLocation: | autophagosome,cytoplasm,cytosol,endoplasmic reticulum,endosome,Golgi apparatus,mitochondrial outer membrane,nucleoplasm,perinuclear region of cytoplasm,peroxisome,plasma membrane |
| ResearchArea: | |
| RRID: | AB_2864054 |
| Background: | Enables 2',3'-cyclic GMP-AMP binding activity; cyclic-di-GMP binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including defense response to other organism; macroautophagy; and positive regulation of interferon-beta production. Acts upstream of or within cellular response to interferon-beta; positive regulation of transcription by RNA polymerase II; and regulation of inflammatory response. Located in several cellular components, including autophagosome; perinuclear region of cytoplasm; and peroxisome. Is expressed in ductus deferens; epididymis; ileum; and prostate gland. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1). |
