Clone 105 (See other available formats) Regulatory Status RUO Other Names F12A2B5, 105 Isotype Mouse IgM, κ Antigen Details Distribution Developing thymic epithelial cells, oligodendrocyte progenitors, neuroendocrine, embryonic neonatal tissue, astrocytoma, glioma, and squamous cell carcinoma. Cell Type Epithelial cells, Oligodendrocytes Biology Area Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers Antigen References 1. Baracskay KL, et al. 2007. GLIA 55:1001.2. Raff MC, et al. 1983. J. Neurosci. 6:1289.3. Fredman P, et al. 1984. Arch. Biochem. Biophys. 2:661.4. Xia CL, et al. 2003. Int. J. Oncol. 23:353.5. Tchoghandjian A, et al. Brain Pathol. 20:211. Gene ID NA UniProt The 105/A2B5 antibody recognizes a membrane protein that is expressed by chicken retinal cells, neuronal cells, ganglia, and spinal cord. In combination with other markers, this antibody can be used to differentiate between type 1 and type 2 astrocytes. The antibody recognizes polysialogangliosides and can be used to monitor glial cell development. A2B5 antigens are expressed by a variety of tumors including glioblastomas. Tumors expressing A2B5 antigen exhibit higher recurrence. The A2B5 antibody can also be used to identify progenitor cells.