Clone 4B2.9 (See other available formats) Regulatory Status RUO Other Names Vγ1 and Vγ2 (Tonegawa nomenclature) Isotype Armenian Hamster IgG Antigen Details Distribution Subset of γ/δ T cells Function Antigen recognition Cell Type T cells Biology Area Adaptive Immunity, Immunology Molecular Family TCRs Antigen References 1. Garcia-Herrera A, et al. 2011. Am. J. Surg. Pathol. 35:1214. 2. Gutierrez A, et al. 2010. J. Clin. Oncol. 28:3816. 3. Zhang X, et al. 2009. Hematology 14:237. Gene ID 110067 In mice, the TCR g locus consists of seven Vg, four Jg and four Cg genes, which are differentially expressed through their lifespan. During fetal and early postnatal life, very few γ/δ T cells express TCR Vγ1.1 or Vγ1.2 chains. In adult mice, however, a major fraction of the γ/δ T cell repertoire comprise either TCR Vγ1.1 or Vγ1.2 chains. The Vγ1.1 gene rearranges almost exclusively with the Jg4-Cg4 genes, while the Vγ1.2 gene preferentially does with Jg1.