serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
别称
PAI;PAI1;PLANH1
中文名称
纤溶酶原激活物抑制剂1
Uniprot
P05121
GeneID
5054
交叉反应(推测)
Human Mouse Rat (Bovine Zebrafish)
氨基酸大小
45kDa
表达氨基酸
1-402aa
Background
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily.This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis.Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Application
Immunology research
Derived from
E.coli
Purification
NI-NTA affinity purification
Formulation
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0.
Shipping
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity
Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin
/
Bioactive
Not tested.
Tag information
With a 6His tag at the N-terminus.
单位
支
规格
10ug 50ug 100ug 1mg
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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