Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Swiss Prot
Q9BSI4
Gene ID
26277
亚细胞定位
Nucleus
宿主
Rabbit
克隆类型
Polyclonal Antibody
亚型
IgG
蛋白分子量
50/39/15kDa
稀释比例
WB 1:1000-3000.
免疫原
A synthetic peptide of human TINF2
Public Immunogen Range
395-445/451aa
纯化方法
Affinity purification
储存液
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存
Store at -20°C. Avoid freeze / thaw cycles.
交叉反应
Human Mouse
应用
WB
规格
50ul 100ul
单位
支
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
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