CLGI, Collagenase inhibitor, EPA, EPO, FLJ90373, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP 1, TIMP1
中文名称
金属肽酶抑制剂1
Uniprot
P01033
GeneID
7076
交叉反应(推测)
Human Mouse Rat (Bovine Pig Sheep Dog Rabbit Horse Macaque Gorilla)
氨基酸大小
23kDa
表达氨基酸
1-207aa
Background
This gene belongs to the TIMP gene family.The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix.In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.Transcription of this gene is highly inducible in response to many cytokines and hormones.In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females.This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Application
Immunology research
Derived from
E.coli
Purification
NI-NTA affinity purification
Formulation
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0.
Shipping
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage
Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity
Purity≥85% as determined by reducing SDS-PAGE.
Bioactive
Not tested.
Tag information
With a 6His tag at the N-terminus.
单位
支
规格
10ug 50ug 100ug 1mg
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these
methods.
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